Epigenetic Library Screen Identifies Abexinostat as Novel Regulator of Adipocytic and Osteoblastic Differentiation of Human Skeletal (Mesenchymal) Stem Cells

The epigenetic mechanisms promoting lineage‐specific commitment of human skeletal (mesenchymal or stromal) stem cells (hMSCs) into adipocytes or osteoblasts are still not fully understood. Herein, we performed an epigenetic library functional screen and identified several novel compounds, including...

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Principais autores:	Dalia Ali, Rimi Hamam, Musaed Alfayez, Moustapha Kassem, Abdullah Aldahmash, Nehad M. Alajez
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 2016-08-01
coleção:	Stem Cells Translational Medicine
Assuntos:	Epigenetic Adipocyte Osteoblast Mesenchymal stem cells Histone deacetylase inhibitors
Acesso em linha:	https://doi.org/10.5966/sctm.2015-0331
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