Intercellular propagation of extracellular signal-regulated kinase activation revealed by in vivo imaging of mouse skin

Extracellular signal-regulated kinase (ERK) is a key effector of many growth signalling pathways. In this study, we visualise epidermal ERK activity in living mice using an ERK FRET biosensor. Under steady-state conditions, the epidermis occasionally revealed bursts of ERK activation patterns where...

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Detalhes bibliográficos

Principais autores:	Toru Hiratsuka, Yoshihisa Fujita, Honda Naoki, Kazuhiro Aoki, Yuji Kamioka, Michiyuki Matsuda
Formato:	Artigo
Idioma:	Inglês
Publicado em:	eLife Sciences Publications Ltd 2015-02-01
coleção:	eLife
Assuntos:	in vivo imaging ERK epidermis cell cycle
Acesso em linha:	https://elifesciences.org/articles/05178
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