Synthesis of oxazoline hydroxamates α,β-unsaturated: Cytotoxic evaluation and inhibitory activity in vitro of histone deacetylases

A series of 28 molecules were synthesized: ten β-hydroxyamides, nine oxazoline esters, and nine oxazoline hydroxamates. Of these compounds, 16 represent new molecules. All synthesized compounds were evaluated against four cancer cell lines (MCF7, PC-3, NCI-H460, and HT-29) and one normal cell line (...

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Autori principali:	Juan J.J. Carrizales-Castillo, María del Rayo Camacho-Corona, Eugenio Hernández-Fernández, Leonardo Adolfo Heredia-Núñez, Selene Lagunas-Rivera, Maria Yolanda Rios, Eder Arredondo-Espinoza, Francisco G. Avalos-Alanís
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2025-03-01
Serie:	Results in Chemistry
Soggetti:	Heterocyclic compounds Oxazolines Hydroxamates Anticancer activity Cytotoxicity Histone deacetylase inhibitors
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2211715625001006
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