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A Novel Hydroxamic Acid-Based Curcumin Derivative as Potent Histone Deacetylase Inhibitor for the Treatment of Glioblastoma

Glioblastoma (GBM) is one of the most common primary and deadliest malignant brain tumor with chemoresistance and poor prognosis. There is a lack of effective chemotherapeutic drug for the treatment of GBM. In this work, we reported the preparation of a histone deacetylase (HDAC) inhibitor, DMC-HA,...

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書目詳細資料
Principais autores: Hao Wang, Lei Shi, Zhimin Wang
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2021-11-01
叢編:Frontiers in Oncology
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在線閱讀:https://www.frontiersin.org/articles/10.3389/fonc.2021.756817/full
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