Integrative dynamic structural biology unveils conformers essential for the oligomerization of a large GTPase

Guanylate binding proteins (GBPs) are soluble dynamin-like proteins that undergo a conformational transition for GTP-controlled oligomerization and disrupt membranes of intracellular parasites to exert their function as part of the innate immune system of mammalian cells. We apply neutron spin echo,...

Ful tanımlama

Kaydedildi:

Detaylı Bibliyografya
Asıl Yazarlar:	Thomas-O Peulen, Carola S Hengstenberg, Ralf Biehl, Mykola Dimura, Charlotte Lorenz, Alessandro Valeri, Julian Folz, Christian A Hanke, Semra Ince, Tobias Vöpel, Bela Farago, Holger Gohlke, Johann P Klare, Andreas M Stadler, Claus AM Seidel, Christian Herrmann
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	eLife Sciences Publications Ltd 2023-06-01
Seri Bilgileri:	eLife
Konular:	single-molecule fluorescence spectroscopy electron paramagnetic resonance small-angle x-ray scattering neutron spin-echo spectroscopy computer simulations large gtpases
Online Erişim:	https://elifesciences.org/articles/79565
Etiketler:	Etiketle Etiket eklenmemiş, İlk siz ekleyin!

Integrative dynamic structural biology unveils conformers essential for the oligomerization of a large GTPase

Benzer Materyaller