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Targeting mutant p53: a key player in breast cancer pathogenesis and beyond

Abstract The p53 mutation is the most common genetic mutation associated with human neoplasia. TP53 missense mutations, which frequently arise early in breast cancer, are present in over thirty percent of breast tumors. In breast cancer, p53 mutations are linked to a more aggressive course of the di...

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Principais autores: Hina Qayoom, Burhan Ul Haq, Shazia Sofi, Nusrat Jan, Asma Jan, Manzoor A. Mir
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2024-10-01
Colecção:Cell Communication and Signaling
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Acesso em linha:https://doi.org/10.1186/s12964-024-01863-9
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