A minimal human physiologically based kinetic model of thyroid hormones and chemical disruption of plasma thyroid hormone binding proteins

The thyroid hormones (THs), thyroxine (T4) and triiodothyronine (T3), are under homeostatic control by the hypothalamic-pituitary-thyroid axis and plasma TH binding proteins (THBPs), including thyroxine-binding globulin (TBG), transthyretin (TTR), and albumin (ALB). THBPs buffer free THs against tra...

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Autors principals:	Anish D. Bagga, Brian P. Johnson, Qiang Zhang
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2023-05-01
Col·lecció:	Frontiers in Endocrinology
Matèries:	thyroid hormone thyroid hormone binding protein thyroxine-binding globulin transthyretin albumin PBK model
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fendo.2023.1168663/full
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