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A minimal human physiologically based kinetic model of thyroid hormones and chemical disruption of plasma thyroid hormone binding proteins

The thyroid hormones (THs), thyroxine (T4) and triiodothyronine (T3), are under homeostatic control by the hypothalamic-pituitary-thyroid axis and plasma TH binding proteins (THBPs), including thyroxine-binding globulin (TBG), transthyretin (TTR), and albumin (ALB). THBPs buffer free THs against tra...

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Detalles Bibliográficos
Principais autores: Anish D. Bagga, Brian P. Johnson, Qiang Zhang
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Endocrinology
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Acceso en liña:https://www.frontiersin.org/articles/10.3389/fendo.2023.1168663/full
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