Targeting Integrin α3 Blocks β1 Maturation, Triggers Endoplasmic Reticulum Stress, and Sensitizes Glioblastoma Cells to TRAIL-Mediated Apoptosis

Glioblastoma (GBM) is a devastating brain cancer for which new effective therapies are urgently needed. GBM, after an initial response to current treatment regimens, develops therapeutic resistance, leading to rapid patient demise. Cancer cells exhibit an inherent elevation of endoplasmic reticulum...

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Detalles Bibliográficos

Autores principales:	Yuki Kuranaga, Bing Yu, Satoru Osuka, Hanwen Zhang, Narra S. Devi, Sejong Bae, Erwin G. Van Meir
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	MDPI AG 2024-04-01
Colección:	Cells
Materias:	brain tumor glioblastoma integrin ER stress death receptor 5
Acceso en línea:	https://www.mdpi.com/2073-4409/13/9/753
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