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Targeting Integrin α3 Blocks β1 Maturation, Triggers Endoplasmic Reticulum Stress, and Sensitizes Glioblastoma Cells to TRAIL-Mediated Apoptosis

Glioblastoma (GBM) is a devastating brain cancer for which new effective therapies are urgently needed. GBM, after an initial response to current treatment regimens, develops therapeutic resistance, leading to rapid patient demise. Cancer cells exhibit an inherent elevation of endoplasmic reticulum...

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Váldodahkkit: Yuki Kuranaga, Bing Yu, Satoru Osuka, Hanwen Zhang, Narra S. Devi, Sejong Bae, Erwin G. Van Meir
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: MDPI AG 2024-04-01
Ráidu:Cells
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Liŋkkat:https://www.mdpi.com/2073-4409/13/9/753
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