Enhancer hijacking at the ARHGAP36 locus is associated with connective tissue to bone transformation

Abstract Heterotopic ossification is a disorder caused by abnormal mineralization of soft tissues in which signaling pathways such as BMP, TGFβ and WNT are known key players in driving ectopic bone formation. Identifying novel genes and pathways related to the mineralization process are important st...

Fuld beskrivelse

Bibliografiske detaljer

Principais autores:	Uirá Souto Melo, Jerome Jatzlau, Cesar A. Prada-Medina, Elisabetta Flex, Sunhild Hartmann, Salaheddine Ali, Robert Schöpflin, Laura Bernardini, Andrea Ciolfi, M-Hossein Moeinzadeh, Marius-Konstantin Klever, Aybuge Altay, Pedro Vallecillo-García, Giovanna Carpentieri, Massimo Delledonne, Melanie-Jasmin Ort, Marko Schwestka, Giovanni Battista Ferrero, Marco Tartaglia, Alfredo Brusco, Manfred Gossen, Dirk Strunk, Sven Geißler, Stefan Mundlos, Sigmar Stricker, Petra Knaus, Elisa Giorgio, Malte Spielmann
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Portfolio 2023-04-01
Serier:	Nature Communications
Online adgang:	https://doi.org/10.1038/s41467-023-37585-8
Tags:	Tilføj Tag Ingen Tags, Vær først til at tagge denne postø!