OXA-23 β-Lactamase Overexpression in Acinetobacter baumannii Drives Physiological Changes Resulting in New Genetic Vulnerabilities

ABSTRACT β-Lactamase expression is the major mechanism of resistance to penicillins, cephalosporins, and carbapenems in the multidrug-resistant (MDR) bacterium Acinetobacter baumannii. In fact, stable high-level expression of at least one β-lactamase has been rapidly increasing and reported to occur...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Jennifer M. Colquhoun, Marjan Farokhyfar, Anna R. Hutcheson, Alexander Anderson, Christopher R. Bethel, Robert A. Bonomo, Anthony J. Clarke, Philip N. Rather
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology 2021-12-01
coleção:	mBio
Assuntos:	Acinetobacter beta-lactamases peptidoglycan
Acesso em linha:	https://journals.asm.org/doi/10.1128/mBio.03137-21
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!