Regression of albuminuria and hypertension and arrest of severe renal injury by a losartan-hydrochlorothiazide association in a model of very advanced nephropathy.

Treatments that effectively prevent chronic kidney disease (CKD) when initiated early often yield disappointing results when started at more advanced phases. We examined the long-term evolution of renal injury in the 5/6 nephrectomy model (Nx) and the effect of an association between an AT-1 recepto...

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Detalhes bibliográficos

Principais autores:	Simone Costa Alarcon Arias, Carla Perez Valente, Flavia Gomes Machado, Camilla Fanelli, Clarice Silvia Taemi Origassa, Thales de Brito, Niels Olsen Saraiva Camara, Denise Maria Avancini Costa Malheiros, Roberto Zatz, Clarice Kazue Fujihara
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2013-01-01
coleção:	PLoS ONE
Acesso em linha:	http://europepmc.org/articles/PMC3576388?pdf=render
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