A local-optimization refinement algorithm in single particle analysis for macromolecular complex with multiple rigid modules

ABSTRACT Single particle analysis, which can be regarded as an average of signals from thousands or even millions of particle projections, is an efficient method to study the three-dimensional structures of biological macromolecules. An intrinsic assumption in single particle analysis is that all th...

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Váldodahkkit:	Hong Shan, Zihao Wang, Fa Zhang, Yong Xiong, Chang-Cheng Yin, Fei Sun
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	Oxford University Press 2015-12-01
Ráidu:	Protein & Cell
Fáttát:	cryo-electron microscopy single particle analysis conformational heterogeneity rigid module local optimization refinement
Liŋkkat:	http://link.springer.com/article/10.1007/s13238-015-0229-2
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