A Method for Using Cell-Penetrating Peptides for Loading Plasmid DNA into Secreted Extracellular Vesicles

The low bioavailability and high toxicity of plasmid DNA (pDNA)-based therapeutics pose challenges for their in vivo application. Extracellular vesicles (EVs) have great potential to overcome these limitations, as they are biocompatible native cargo carriers. Various methods for loading pDNA into EV...

תיאור מלא

מידע ביבליוגרפי

Principais autores:	Jekaterina Nebogatova, Heleri Heike Härk, Anett Puskar, Ly Porosk, Paolo Guazzi, Moataz Dowaidar, Ülo Langel, Kaido Kurrikoff
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	MDPI AG 2023-12-01
סדרה:	Biomolecules
נושאים:	extracellular vesicles gene therapy nucleic acid therapeutics drug delivery system cell-penetrating peptides
גישה מקוונת:	https://www.mdpi.com/2218-273X/13/12/1751
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!