ALD-R491 regulates vimentin filament stability and solubility, cell contractile force, cell migration speed and directionality

Metastasizing cells express the intermediate filament protein vimentin, which is used to diagnose invasive tumors in the clinic. However, the role of vimentin in cell motility, and if the assembly of non-filamentous variants of vimentin into filaments regulates cell migration remains unclear. We obs...

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Detalhes bibliográficos

Principais autores:	Hyejeong Rosemary Kim, Samantha J. Warrington, Ana López-Guajardo, Khairat Al Hennawi, Sarah L. Cook, Zak D. J. Griffith, Deebie Symmes, Tao Zhang, Zhipeng Qu, Ying Xu, Ruihuan Chen, Annica K. B. Gad
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2022-11-01
Colecção:	Frontiers in Cell and Developmental Biology
Assuntos:	vimentin vimentin assembly intermediate filaments (IFs) cytoskeletal organization contractile forces fluorescence recovery after photobleaching (FRAP)
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fcell.2022.926283/full
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