Phenylpiperazine 5,5-Dimethylhydantoin Derivatives as First Synthetic Inhibitors of Msr(A) Efflux Pump in <i>Staphylococcus epidermidis</i>

Herein, 15 phenylpiperazine 3-benzyl-5,5-dimethylhydantoin derivatives (<b>1</b>–<b>15</b>) were screened for modulatory activity towards Msr(A) efflux pump present in <i>S. epidermidis</i> bacteria. Synthesis, crystallographic analysis, biological studies in vitro and structure–activity relationshi...

पूर्ण विवरण

ग्रंथसूची विवरण

मुख्य लेखकों:	Karolina Witek, Gniewomir Latacz, Aneta Kaczor, Joanna Czekajewska, Ewa Żesławska, Anna Chudzik, Elżbieta Karczewska, Wojciech Nitek, Katarzyna Kieć-Kononowicz, Jadwiga Handzlik
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	MDPI AG 2020-08-01
श्रृंखला:	Molecules
विषय:	<i>Staphylococcus epidermidis</i> efflux pump Msr(A) phenylpiperazine 5,5-dimethylhydantoins efflux pump inhibitors EPIs
ऑनलाइन पहुंच:	https://www.mdpi.com/1420-3049/25/17/3788
टैग:	टैग जोड़ें कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!