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Evolutionary diversification of the HAP2 membrane insertion motifs to drive gamete fusion across eukaryotes.

HAPLESS2 (HAP2) is a broadly conserved, gamete-expressed transmembrane protein that was shown recently to be structurally homologous to viral class II fusion proteins, which initiate fusion with host cells via insertion of fusion loops into the host membrane. However, the functional conformation of...

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主要な著者: Juliette Fedry, Jennifer Forcina, Pierre Legrand, Gérard Péhau-Arnaudet, Ahmed Haouz, Mark Johnson, Felix A Rey, Thomas Krey
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science (PLoS) 2018-08-01
シリーズ:PLoS Biology
オンライン・アクセス:https://doi.org/10.1371/journal.pbio.2006357
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