Evolutionary diversification of the HAP2 membrane insertion motifs to drive gamete fusion across eukaryotes.
HAPLESS2 (HAP2) is a broadly conserved, gamete-expressed transmembrane protein that was shown recently to be structurally homologous to viral class II fusion proteins, which initiate fusion with host cells via insertion of fusion loops into the host membrane. However, the functional conformation of...
Kaydedildi:
| Asıl Yazarlar: | , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Public Library of Science (PLoS)
2018-08-01
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| Seri Bilgileri: | PLoS Biology |
| Online Erişim: | https://doi.org/10.1371/journal.pbio.2006357 |
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