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Dyskerin and telomerase RNA component are sex-differentially associated with outcomes and Sunitinib response in patients with clear cell renal cell carcinoma

Abstract Background Clear cell renal cell carcinoma (ccRCC) displays sex-biased incidence, outcomes, molecular alterations and treatment efficacy; however, clinical managements are largely identical in male and female patients. Moreover, many biomarkers have been identified as predictors for ccRCC o...

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Principais autores: Huiyang Yuan, Xin Qin, Qingya Yang, Li Liu, Zhiqing Fang, Yidong Fan, Dawei Xu
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2023-07-01
Serier:Biology of Sex Differences
Fag:
ccRCC
DKC1
Sex difference
Sunitinib
TERC
Telomerase
Online adgang:https://doi.org/10.1186/s13293-023-00526-7
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