CircGRHL2 suppresses EMT and enhances sunitinib sensitivity in ccRCC via the miR-330-5p/FBXO21 axis

Abstract Clear cell renal cell carcinoma (ccRCC) is one of the most common cancers in the urinary system. Studies have shown that circRNAs have potential effects in a variety of human tumors. Studying the important signaling pathways and therapeutic targets of circRNAs is essential to increase under...

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Detalhes bibliográficos

Principais autores:	Jie Gao, Huibao Yao, Qiancheng Mao, Chu Liu, Yuanshan Cui, Junjie Zhao, Jian Ma, Jitao Wu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Springer 2026-04-01
coleção:	Cellular and Molecular Life Sciences
Assuntos:	circGRHL2 EMT Sunitinib sensitivity ccRCC
Acesso em linha:	https://doi.org/10.1007/s00018-026-06102-7
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