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Inhibition of NLRP3 inflammasome activation alleviated liver injury and wasting effect in tumor-bearing mice

Abstract This study is designed to evaluate the changes in tumor-bearing mice, as well as to assess the role of NLRP3 in muscle atrophy and its function in the liver of tumor-bearing mice. In this study, RNA-seq data from the liver of Colon26 (C26) tumor-bearing mice were used to perform pathway enr...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Shuaihui Wu, Qian Cheng, Yang Shi, Mingjun Liu, Kai Tan, Bo Liao
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Portfolio 2025-11-01
Schriftenreihe:Scientific Reports
Schlagworte:
Online-Zugang:https://doi.org/10.1038/s41598-025-23323-1
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