Intracellular signalling pathways and cytoskeletal functions converge on the psoriasis candidate gene CCHCR1 expressed at P-bodies and centrosomes

Abstract Background CCHCR1 (Coiled-Coil α-Helical Rod protein 1) is a putative psoriasis candidate gene with the risk alleles CCHCR1*WWCC and *Iso3, the latter inhibiting the translation of isoform 1. CCHCR1 was recently shown to be a centrosomal protein, as well as a component of cytoplasmic proces...

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Detalhes bibliográficos

Principais autores:	Mari H. Tervaniemi, Shintaro Katayama, Tiina Skoog, H. Annika Siitonen, Jyrki Vuola, Kristo Nuutila, Kristiina Tammimies, Sari Suomela, Esko Kankuri, Juha Kere, Outi Elomaa
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2018-06-01
coleção:	BMC Genomics
Assuntos:	CCHCR1 PSORS1 Centrosome Cytoskeleton P-body Cell adhesion
Acesso em linha:	http://link.springer.com/article/10.1186/s12864-018-4810-y
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