Phosphatase PTPN22 functions as an adaptor in the mTORC2 complex
Abstract mTOR (mechanistic target of rapamycin) kinase is a pivotal regulator of cellular growth and metabolism, integrating signals from nutrients and growth factors. It functions through the assembly of two distinct complexes, mTORC1 and mTORC2, which differ in their substrate specificity and regu...
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| Hoofdauteurs: | , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Springer Nature
2025-09-01
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| Reeks: | EMBO Reports |
| Onderwerpen: | |
| Online toegang: | https://doi.org/10.1038/s44319-025-00576-5 |
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