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Consideration of Surrogate Endpoints for Overall Survival Associated With First-Line Immunotherapy in Extensive-Stage Small Cell Lung Cancer

BackgroundThe combination of immune checkpoint inhibitors (ICIs) and chemotherapy is known to improve overall survival (OS) in patients with extensive-stage small cell lung cancer (ES-SCLC). ICIs have different response patterns and survival kinetics characteristics from those of the traditional che...

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Principais autores: Shuang Zhang, Shuang Li, Yanan Cui, Peiyan Zhao, Xiaodan Sun, Ying Cheng
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021-07-01
Serier:Frontiers in Oncology
Fag:
small-cell lung cancer
surrogate endpoints
survival
immunotherapy
restricted mean survival time (RMST)
Online adgang:https://www.frontiersin.org/articles/10.3389/fonc.2021.696010/full
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