Palliative long-term abdominal drains vs. large volume paracentesis for refractory ascites secondary to cirrhosis: protocol for a definitive randomised controlled trial (REDUCe2 study)

Abstract Background Ascites remains the most common complication of cirrhosis and a frequent reason for hospitalisation in advanced chronic liver disease (ACLD). Ascites is associated with significant symptom burden, caregiver workload and poor health-related quality of life (HRQoL). Once refractory...

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Ngā kaituhi matua:	Yazan Haddadin, Vasso Anagnostopoulou, Stephen Bremner, Helena Harder, Rachel Starkings, Debbie Lambert, Alison Porges, Nicky Perry, Wendy Wood, Amy Arbon, Heather Gage, Matthew Glover, Lucia Macken, Malcolm Johnston, Bhaskar Ganai, Dhiraj Joshi, Ben Hudson, Claire Butler, Alison Richardson, Mark Wright, Wendy Prentice, Alastair O’Brien, Joan Bedlington, Shani Steer, Tom Gaskin, Sumita Verma
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	BMC 2025-06-01
Rangatū:	Trials
Ngā marau:	Ascites End-stage liver disease Paracentesis Palliative care Quality of life Caregivers
Urunga tuihono:	https://doi.org/10.1186/s13063-025-08873-z
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!