Palliative long-term abdominal drains vs. large volume paracentesis for refractory ascites secondary to cirrhosis: protocol for a definitive randomised controlled trial (REDUCe2 study)

Abstract Background Ascites remains the most common complication of cirrhosis and a frequent reason for hospitalisation in advanced chronic liver disease (ACLD). Ascites is associated with significant symptom burden, caregiver workload and poor health-related quality of life (HRQoL). Once refractory...

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Hlavní autoři:	Yazan Haddadin, Vasso Anagnostopoulou, Stephen Bremner, Helena Harder, Rachel Starkings, Debbie Lambert, Alison Porges, Nicky Perry, Wendy Wood, Amy Arbon, Heather Gage, Matthew Glover, Lucia Macken, Malcolm Johnston, Bhaskar Ganai, Dhiraj Joshi, Ben Hudson, Claire Butler, Alison Richardson, Mark Wright, Wendy Prentice, Alastair O’Brien, Joan Bedlington, Shani Steer, Tom Gaskin, Sumita Verma
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2025-06-01
Edice:	Trials
Témata:	Ascites End-stage liver disease Paracentesis Palliative care Quality of life Caregivers
On-line přístup:	https://doi.org/10.1186/s13063-025-08873-z
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