Risks of non-breast, non-ovarian cancers for BRCA1 and BRCA2 pathogenic variant carriers: a prospective cohort study

Abstract Background The non-breast non-ovarian cancers associated with BRCA1 and BRCA2 pathogenic variants (PVs) are controversial. We aimed to examine this using a prospective cohort design. Methods This study included 1260 BRCA1 and 1058 BRCA2 PV carriers (91% were females) from two consortia: the...

وصف كامل

التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	Ruotong Yang, Robert J. MacInnis, Roger L. Milne, Tu Nguyen-Dumont, Whitney F. Maxwell, Jeanine M. Genkinger, Gord Glendon, The Kathleen Cuningham Foundation Consortium for Research Into Familial Breast Cancer (kConFab), Eric A. Ross, Irene L. Andrulis, Sarah V. Colonna, Mary Daly, Esther M. John, Allison W. Kurian, Mary Beth Terry, John L. Hopper, Melissa C. Southey, Kelly-Anne Phillips, Shuai Li
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	BMC 2026-03-01
سلاسل:	BMC Medicine
الموضوعات:	BRCA1 BRCA2 Prospective study Penetrance Cancer risk
الوصول للمادة أونلاين:	https://doi.org/10.1186/s12916-026-04753-8
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!