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Endometriosis in Carriers of a Pathogenic Variant in <i>BRCA1</i> or <i>BRCA2</i>: A Descriptive Analysis of a Large Multicentral <i>BRCA</i> Carrier Cohort

<b>Background:</b> Endometriosis affects an estimated 10% of reproductive-aged women and is associated with increased ovarian cancer risk. While <i>BRCA1/2</i> mutations are established risk factors for ovarian cancer, their association with endometriosis remains unclear. This study aimed to charact...

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Principais autores: Aghaghia Mokhber, Brynne Stewart, Kathryn L. Terry, Jacek Gronwald, Cezary Cybulski, Raymond H. Kim, Beth Y. Karlan, Louise Bordeleau, Teresa Ramón y Cajal, Tuya Pal, Andrea Eisen, Fergus J. Couch, Dana Zakalik, Nadine Tung, Robert Fruscio, William D. Foulkes, Amber M. Aeilts, Ping Sun, Jan Lubiński, Steven Narod, Joanne Kotsopoulos
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2025-12-01
coleção:Current Oncology
Assuntos:
<i>BRCA</i> mutations
endometriosis
ovarian cancer
prevalence
reproductive epidemiology
Acesso em linha:https://www.mdpi.com/1718-7729/32/12/675
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