MicroRNAs located in the Hox gene clusters are implicated in huntington's disease pathogenesis.

Transcriptional dysregulation has long been recognized as central to the pathogenesis of Huntington's disease (HD). MicroRNAs (miRNAs) represent a major system of post-transcriptional regulation, by either preventing translational initiation or by targeting transcripts for storage or for degradation...

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מידע ביבליוגרפי

Principais autores:	Andrew G Hoss, Vinay K Kartha, Xianjun Dong, Jeanne C Latourelle, Alexandra Dumitriu, Tiffany C Hadzi, Marcy E Macdonald, James F Gusella, Schahram Akbarian, Jiang-Fan Chen, Zhiping Weng, Richard H Myers
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Public Library of Science (PLoS) 2014-02-01
סדרה:	PLoS Genetics
גישה מקוונת:	https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1004188&type=printable
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