MicroRNAs located in the Hox gene clusters are implicated in huntington's disease pathogenesis.

Transcriptional dysregulation has long been recognized as central to the pathogenesis of Huntington's disease (HD). MicroRNAs (miRNAs) represent a major system of post-transcriptional regulation, by either preventing translational initiation or by targeting transcripts for storage or for degradation...

Disgrifiad llawn

Manylion Llyfryddiaeth

Prif Awduron:	Andrew G Hoss, Vinay K Kartha, Xianjun Dong, Jeanne C Latourelle, Alexandra Dumitriu, Tiffany C Hadzi, Marcy E Macdonald, James F Gusella, Schahram Akbarian, Jiang-Fan Chen, Zhiping Weng, Richard H Myers
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Public Library of Science (PLoS) 2014-02-01
Cyfres:	PLoS Genetics
Mynediad Ar-lein:	https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1004188&type=printable
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!