Single cell analyses of cancer cells identified two regulatorily and functionally distinct categories in differentially expressed genes among tumor subclones

To explore the feature of cancer cells and tumor subclones, we analyzed 101,065 single-cell transcriptomes from 12 colorectal cancer (CRC) patients and 92 single cell genomes from one of these patients. We found cancer cells, endothelial cells and stromal cells in tumor tissue expressed much more ge...

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Detaylı Bibliyografya

Asıl Yazarlar:	Wei Cao, Xuefei Wang, Kaiwen Luo, Yang Li, Jiahong Sun, Ruqing Fu, Qi Zhang, Ni Hong, Edwin Cheung, Wenfei Jin
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	Elsevier 2024-03-01
Seri Bilgileri:	Heliyon
Konular:	Colorectal cancer Single cell RNA sequencing Single cell whole genome sequencing Copy number variations Differentially expressed gene Cell-cell communication
Online Erişim:	http://www.sciencedirect.com/science/article/pii/S2405844024041021
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