Reduced sialylation of airway mucin impairs mucus transport by altering the biophysical properties of mucin
Abstract Mucus stasis is a pathologic hallmark of muco-obstructive diseases, including cystic fibrosis (CF). Mucins, the principal component of mucus, are extensively modified with hydroxyl (O)-linked glycans, which are largely terminated by sialic acid. Sialic acid is a negatively charged monosacch...
Salvato in:
| Autori principali: | , , , , , , , , |
|---|---|
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Portfolio
2024-07-01
|
| Serie: | Scientific Reports |
| Accesso online: | https://doi.org/10.1038/s41598-024-66510-2 |
| Tags: |
Nessun Tag, puoi essere il primo ad aggiungerne!!
|