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Mycobacterium tuberculosis Transcription Factor EmbR Regulates the Expression of Key Virulence Factors That Aid in Ex Vivo and In Vivo Survival

ABSTRACT Mycobacterium tuberculosis encodes ~200 transcription factors that modulate gene expression under different microenvironments in the host. Even though high-throughput chromatin immunoprecipitation sequencing and transcriptome sequencing (RNA-seq) studies have identified the regulatory netwo...

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Principais autores: Suresh Kumar, Mehak Zahoor Khan, Neha Khandelwal, Chen Chongtham, Biplab Singha, Ankita Dabla, Debashree Behera, Archana Singh, Balasubramanian Gopal, G. Aneeshkumar Arimbasseri, Siddhesh S. Kamat, Vinay Kumar Nandicoori
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2022-06-01
Serier:mBio
Fag:
transcription
transcription factors
hypoxia
mycobacteria
tuberculosis
granuloma
Online adgang:https://journals.asm.org/doi/10.1128/mbio.03836-21
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