Development of an RNA aptamer as a therapeutic agent for synucleinopathies
Abstract The aggregation of α-synuclein (αSyn), a 140-mer protein, has been implicated in the pathogenesis of Parkinson’s disease, multiple system atrophy, and dementia with Lewy bodies. KTKEGV pseudo-repeats (KRs) in the sequence of αSyn are key mediators of its prion-like propagation and neurodege...
Salvato in:
| Autori principali: | , , , , , , , , , , , , |
|---|---|
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Portfolio
2026-07-01
|
| Serie: | Nature Communications |
| Accesso online: | https://doi.org/10.1038/s41467-026-75209-z |
| Tags: |
Nessun Tag, puoi essere il primo ad aggiungerne!!
|