Exploring novel ligands for mGluR5: Design, computational analysis, and protein-ligand interaction studies
Abstracts: Metabotropic glutamate receptors (mGluRs) are G-protein-coupled receptors activated by glutamate. A series of 90 novel compounds have been assessed as mGluR5 receptor antagonists. These compounds, selected post-ADMET filtering according to Lipinski's rule of five, represent structurally i...
שמור ב:
| Principais autores: | , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Elsevier
2024-12-01
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| סדרה: | Chemical Physics Impact |
| נושאים: | |
| גישה מקוונת: | http://www.sciencedirect.com/science/article/pii/S2667022424002354 |
| תגים: |
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