Epo/EpoR signaling in osteoprogenitor cells is essential for bone homeostasis and Epo-induced bone loss

Abstract High erythropoietin (Epo) levels are detrimental to bone health in adult organisms. Adult mice receiving high doses of Epo lose bone mass due to suppressed bone formation and increased bone resorption. In humans, high serum Epo levels are linked to fractures in elderly men. Our earlier stud...

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Principais autores:	Martina Rauner, Marta Murray, Sylvia Thiele, Deepika Watts, Drorit Neumann, Yankel Gabet, Lorenz C. Hofbauer, Ben Wielockx
Format:	Artigo
Jezik:	Inglês
Izdano:	Nature Publishing Group 2021-09-01
Serija:	Bone Research
Online dostop:	https://doi.org/10.1038/s41413-021-00157-x
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