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Enteric neural stem cell transplant restores gut motility in mice with Hirschsprung disease

The goal of this study was to determine if transplantation of enteric neural stem cells (ENSCs) can rescue the enteric nervous system, restore gut motility, reduce colonic inflammation, and improve survival in the Ednrb-KO mouse model of Hirschsprung disease (HSCR). ENSCs were isolated from mouse in...

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書誌詳細
主要な著者: Ahmed A. Rahman, Takahiro Ohkura, Sukhada Bhave, Weikang Pan, Kensuke Ohishi, Leah Ott, Christopher Han, Abigail Leavitt, Rhian Stavely, Alan J. Burns, Allan M. Goldstein, Ryo Hotta
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical investigation 2024-09-01
シリーズ:JCI Insight
主題:
オンライン・アクセス:https://doi.org/10.1172/jci.insight.179755
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