ZAB260: A novel and potent antibacterial agent targeting DNA gyrase

DNA gyrase and topoisomerase IV are well-established targets for antibiotics. These enzymes play crucial roles in managing the topology of DNA, which is essential for bacterial survival. ZAB260, an inhibitor of bacterial DNA gyrase, is a dihydroquinoline carbonitrile-based antibacterial agent, which...

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Hlavní autoři:	Sanjay Kumar, Bhaumin Patel, Jinal Trivedi, Purvi Vyas, Vishwanath Pawar, Poonam Giri, S. Sachchidanand, Kasinath Viswanathan, Rajiv Sharma, Mukul Jain, Pravin Iyer, Jigar Desai
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2025-06-01
Edice:	The Microbe
Témata:	ZAB260 Minimum inhibitory concentration Post antibiotic effect Lung infection
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2950194625001116
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