Leveraging multi-omics data to infer regulators of mRNA 3’ end processing in glioblastoma

Alterations in mRNA 3’ end processing and polyadenylation are widely implicated in the biology of many cancer types, including glioblastoma (GBM), one the most aggressive tumor types. Although several RNA-binding proteins (RBPs) responsible for alternative polyadenylation (APA) were identified from...

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Autors principals:	Aleksei Mironov, Lorenzo Franchitti, Shreemoyee Ghosh, Marie-Francoise Ritz, Gregor Hutter, Michele De Bortoli, Mihaela Zavolan
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2024-08-01
Col·lecció:	Frontiers in Molecular Biosciences
Matèries:	glioblastoma TCGA ENCODE RBP alternative polyadenylation
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fmolb.2024.1363933/full
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