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Targeting Transient Receptor Potential (TRP) Channels, Mas-Related G-Protein-Coupled Receptors (Mrgprs), and Protease-Activated Receptors (PARs) to Relieve Itch

Itch (pruritus) is a sensation in the skin that provokes the desire to scratch. The sensation of itch is mediated through a subclass of primary afferent sensory neurons, termed pruriceptors, which express molecular receptors that are activated by itch-evoking ligands. Also expressed in pruriceptors...

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Principais autores: Merab G. Tsagareli, Taylor Follansbee, Mirela Iodi Carstens, Earl Carstens
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2023-12-01
Series:Pharmaceuticals
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Acceso en liña:https://www.mdpi.com/1424-8247/16/12/1707
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