A ketogenic diet sensitizes pancreatic cancer to glutamine metabolism inhibitors

Summary: Pancreatic cancer is the third leading cause of cancer-related death in the United States. Current chemotherapy options provide limited benefits. Emerging evidence suggests that a ketogenic diet (KD) exerts anti-tumor effects by reprogramming tumor metabolism and revealing therapeutic vulne...

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Үндсэн зохиолчид:	Omid Hajihassani, Asael Roichman, Jacob A. Boyer, Michal MacArthur, Ricardo Cordova, Alexander Loftus, Christina S. Boutros, Jonathan J. Hue, Parnian Naji, Soubhi Tahhan, Peter Gallagher, William Beegan, Danyal Shah, James Choi, Nimat Manzoor, Shihong Lei, Christine Kim, Moeez Rathore, Ishan Shah, Kevin Lebo, Helen Cheng, Anusha Mudigonda, Craig Hunter, Mehrdad Zarei, Sydney Alibeckoff, Karen Ji, Hallie Graor, Masaru Miyagi, Ali Vaziri-Gohar, Henri Brunengraber, Rui Wang, Peder J. Lund, Luke D. Rothermel, Joshua D. Rabinowitz, Jordan M. Winter
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Elsevier 2026-05-01
Цуврал:	Cell Reports Medicine
Нөхцлүүд:	pancreatic cancer ketogenic diet glutamine metabolism targeted therapy chemotherapy combination therapy
Онлайн хандалт:	http://www.sciencedirect.com/science/article/pii/S2666379126001874
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