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Small molecule-induced destabilization of β-catenin and RAS is the ideal strategies for suppressing colorectal cancer

Background Mutations of adenomatous polyposis coli (APC) and KRAS play essential roles in the development of colorectal cancer (CRC) by forming an abnormal colon morphology. Despite intensive efforts to discover therapeutic strategies to re-transform cancer cells into normal cells, no effective appr...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Yonghyo Kim, Myoung-Hee Kang, Geon-Woo Kim, Yong-Hee Cho
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Organoid Society 2023-03-01
Schriftenreihe:Organoid
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Online-Zugang:http://j-organoid.org/upload/pdf/organoid-2023-3-e4.pdf
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