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Cytotoxic Effects on Breast Cancer Cell Lines of Chalcones Derived from a Natural Precursor and Their Molecular Docking Analysis

This study aimed to determine the in vitro cytotoxicity and understand possible cytotoxic mechanisms via an in silico study of eleven chalcones synthesized from two acetophenones. Five were synthesized from a prenylacetophenone isolated from a plant that grows in the Andean region of the Atacama Des...

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Gardado en:
Principais autores: Luis Bustos, Carlos Echiburú-Chau, Alejandro Castro-Alvarez, Ben Bradshaw, Mario J. Simirgiotis, Marco Mellado, Claudio Parra, Mauricio Cuellar
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2022-07-01
Series:Molecules
Assuntos:
antioxidant
bioactive compounds
breast cancer
cytotoxic
molecular docking
<i>Senecio nutans</i>
Acceso en liña:https://www.mdpi.com/1420-3049/27/14/4387
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