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NK cell activity in the tumor microenvironment

The formation of an immunosuppressive tumor microenvironment (TME) impairs natural killer (NK) cell infiltration and persistence within tumor tissue and significantly diminishes NK-mediated cytotoxicity. This presents a substantial barrier to the efficacy of NK cell therapy in solid tumors. Current...

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Bibliografische Detailangaben
Hauptverfasser: A. V. Kuznetsova, X. A. Glukhova, I. P. Beletsky, A. A. Ivanov
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2025-05-01
Schriftenreihe:Frontiers in Cell and Developmental Biology
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Online-Zugang:https://www.frontiersin.org/articles/10.3389/fcell.2025.1609479/full
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