HexSDF Is Required for Synthesis of a Novel Glycolipid That Mediates Daptomycin and Bacitracin Resistance in C. difficile

ABSTRACT Clostridioides difficile is a Gram-positive opportunistic pathogen responsible for 250,000 hospital-associated infections, 12,000 hospital-associated deaths, and $1 billion in medical costs in the United States each year. There has been recent interest in using a daptomycin analog, surotomy...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Anthony G. Pannullo, Ziqiang Guan, Howard Goldfine, Craig D. Ellermeier
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology 2023-04-01
Edice:	mBio
Témata:	two-component regulatory system cell envelope signal transduction gene expression glycolipid synthesis membrane biogenesis
On-line přístup:	https://journals.asm.org/doi/10.1128/mbio.03397-22
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!