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Mesenchymal stem cells added to second-line therapy improve response and failure-free survival in steroid-refractory acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation: A meta-analysis of randomized controlled trials

BackgroundSteroid-refractory acute graft-versus-host disease (aGVHD) remains a major cause of morbidity and mortality after allogeneic hematopoietic stem cell transplantation (allo-HSCT), with limited effective treatment options. Mesenchymal stem cells (MSCs) have emerged as a promising therapeutic...

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Detalles Bibliográficos
Principais autores: Man Xiao, Yinghu Yan, Rui Zhang, Dan Wang, Li Wang, Yameng Zhao, Jinhong Yang
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2025-11-01
Series:Frontiers in Oncology
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Acceso en liña:https://www.frontiersin.org/articles/10.3389/fonc.2025.1704963/full
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