Efficacy and safety of mitoxantrone hydrochloride liposome-containing regimens in treating refractory/relapsed acute myeloid leukemia

Abstract Background Despite the poor prognosis for patients with relapsed/refractory (R/R) acute myeloid leukemia (AML), an optimal treatment strategy remains undefined. Mitoxantrone (MIT) is widely used to treat R/R AML. Methods This prospective, single-center, open-label study assessed the efficac...

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Hlavní autoři:	Ni Lu, Li Liu, Yigeng Cao, Rongli Zhang, Weihua Zhai, Xin Chen, Qiaoling Ma, Donglin Yang, Aiming Pang, Jialin Wei, Yi He, Sizhou Feng, Mingzhe Han, Erlie Jiang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Springer 2025-05-01
Edice:	Discover Oncology
Témata:	Acute myeloid leukemia Relapsed/refractory acute myeloid leukemia Mitoxantrone hydrochloride liposome Allogeneic hematopoietic stem cell transplantation Composite complete remission
On-line přístup:	https://doi.org/10.1007/s12672-025-02526-y
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