Proinflammatory transcriptomic and kinomic alterations in astrocytes derived from patients with familial Alzheimer's disease

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by profound neuronal and cognitive decline, with increasing evidence implicating astrocyte dysfunction in disease pathology. While traditional therapeutic approaches have primarily targeted neurons, the crucial role o...

وصف كامل

التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	Benjamin Siciliano, Nicholas D. Henkel, William G. Ryan V, Ali Sajid Imami, John M. Vergis, Chongchong Xu, Taylen O. Arvay, Smita Sahay, Priyanka Pulvender, Abdul-rizaq Hamoud, Chadwick Hales, Robert E. McCullumsmith, Zhexing Wen
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	Elsevier 2025-08-01
سلاسل:	Brain, Behavior, & Immunity - Health
الموضوعات:	Alzheimer's disease Familial Alzheimer's disease Astrocyte dysfunction Multiomic analysis Transcriptomics Kinomics
الوصول للمادة أونلاين:	http://www.sciencedirect.com/science/article/pii/S2666354625001024
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!