Glyoxalase System in Breast and Ovarian Cancers: Role of MEK/ERK/SMAD1 Pathway
The glyoxalase system, comprising GLO1 and GLO2 enzymes, is integral in detoxifying methylglyoxal (MGO) generated during glycolysis, with dysregulation implicated in various cancer types. The MEK/ERK/SMAD1 signaling pathway, crucial in cellular processes, influences tumorigenesis, metastasis, and an...
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| Formato: | Artigo |
| Lenguaje: | Inglês |
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MDPI AG
2024-05-01
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| Colección: | Biomolecules |
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| Acceso en línea: | https://www.mdpi.com/2218-273X/14/5/584 |
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